Where can I get consequence annotations for the 1000 genome variants

1000 genomes data sets are available at both Ensembl and UCSC Genome Browser

These browsers get the 1000 genomes data from dbSNP so they may not always contain the most recent 1000 genomes variant release but the 1000 genomes project has its own version of Ensembl which contains more recent variant sets. We also have a frozen version of our browser for the pilot data set at http://pilotbrowser.1000genomes.org

The pilot data for the 1000 genomes project was all mapped to NCBI36/hg18 build of the human assembly but once the data had been loaded into dbSNP it was mapped to GRCh37/hg19 and these are the coordinates that Ensembl and UCSC present to the world but this does mean that the coordinates from the pilot data on the 1000 genomes ftp site will be different to the coordinates presented in Ensembl and UCSC.

It also sometimes takes time for 1000 genomes variants to be loaded by dbSNP and for those rs numbers to get back to the 1000 genomes browser so if you are unable to find a particular rs number from dbSNP in the 1000 genomes browser this is most likely due to an issue with the syncing of ids.

Ensembl can also provides consequence information for the variants. The variants that are loaded into the Ensembl database and have consequence types assigned and displayed on the Variation view. Ensembl can also offer consequence predictions using their Variant effect predictor.

You can also see individual genotype information in the Ensembl browser by looking at the Individual Genotypes section of the page from the menu on the left hand side.